Replication of linear plasmids in bacteria by Prof. George Chaconas University of Calgary, Canada

The 43-minute multimedia lecture titled "Replication of Linear Plasmids in Bacteria" by Prof. George Chaconas from the University of Calgary, Canada, provides an in-depth exploration of the replication mechanisms of linear DNA in diverse bacteria, focusing on organisms like Streptomyces and Borrelia.The lecture addresses the "end replication" problem and solutions to it, including the replication pathways for specific viruses and bacteria such as Adenovirus, Bacillus phage f29, Streptomyces, and Borrelia burgdorferi. The lecture delves into the molecular processes involved in DNA replication, including the recruitment and deoxynucleotidylation of terminal proteins, as well as the mechanisms of telomere resolution by proteins like ResT. Additionally, Prof. George Chaconas discusses genome plasticity, sequence scrambling, and telomere exchanges, offering insights into the dynamic nature of bacterial genetic systems.For further details, watch a video